AS1411 Resource Literature
- In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation
- AGRO100 inhibits activation of nuclear factor-KB (NF-KB) by forming a complex with NF-KB essential modulator (NEMO) and nucleolin
- Oncogenic Synergism between ErbB1, Nucleolin, and Mutant Ras
- A New Paradigm for Aptamer Therapeutic AS1411 Action: Uptake by Macropinocytosis and Its Stimulation by a Nucleolin-Dependent Mechanism
- AS1411 Alters the Localization of a Complex Containing Protein Arginine Methyltransferase 5 and Nucleolin
- G-quadruplex oligonucleotide AS1411 as a cancer-targeting agent: Uses and mechanisms (Abstract)
- Long-term outcomes of responders in a randomized, controlled phase II trial of aptamer AS1411 in AML. (Abstract)
- A phase II trial of AS1411 (a novel nucleolin-targeted DNA aptamer) in metastatic renal cell carcinoma
- Extended phase I study of AS1411 in renal and non-small cell lung cancers
- Randomized phase II trial of the nucleolin targeting aptamer AS1411 combined with high-dose cytarabine in relapsed/refractory acute myeloid leukemia (AML) (Abstract)
- A phase II, single-arm study of AS1411 in metastatic renal cell carcinoma (RCC). (Abstract)
- Long-term outcomes of responders in a randomized, controlled phase II trial of aptamer AS1411 in AML. (Abstract)
- A phase I study of AGRO100 in advanced cancer (Abstract)
- Extended phase I study of AS1411 in renal and non-small cell lung cancers (Abstract)
- AS1411: A potential targeted therapy for neuroblastoma
- Biophysical and biological properties of quadruplex oligodeoxyribonucleotides
- Cancer-selective antiproliferative activity is a general property of some G-rich oligodeoxynucleotides
- Resolution and characterization of the structural polymorphism of a single quadruplex-forming sequence
- Antiproliferative Activity of G-rich Oligonucleotides Correlates with Protein Binding*
- Apoptosis in Leukemia Cells Is Accompanied by Alterations in the Levels and Localization of Nucleolin*
- Mechanistic studies of anticancer aptamer AS1411 reveal a novel role for nucleolin in regulating Rac1 activation
- Impact of AS1411 on Mechanistic Target of Rapamycin Complexes 1 and 2 (mTORC1/2) Activity
- Targeted Gold Nanoparticle–Oligonucleotide Contrast Agents in Combination with a New Local Voxel-Wise MRI Analysis Algorithm for In Vitro Imaging of Triple-Negative Breast Cancer
- Discovery and Development of the G-rich Oligonucleotide AS1411 as a Novel Treatment for Cancer
- A phase II trial of the nucleolin-targeted DNA aptamer AS1411 in metastatic refractory renal cell carcinoma
- AS1411-conjugated gold nanospheres and their potential for breast cancer therapy
- Randomized phase II trial of the nucleolin targeting aptamer AS1411 combined with high-dose cytarabine in relapsed/refractory acute myeloid leukemia (AML)